AP Biology Help [Cri Du Chat]?

[Sekikawa (??)]

Am I missing anything else? I really need more information on How To Avoid... Please help if you know more about this -Thanks!

How can Cri Du Chat be treated?

My Answer:
• Care is supportive. No treatment is available for cri-du-chat syndrome.
• Genetic counseling is indicated.
oFemale patients are fertile and can deliver viable affected offspring, with an estimated recurrence risk of 50%.
oRecurrence risk for a de novo case is 1% or less. Rare recurrences in chromosomally healthy parents are probably the result of gonadal mosaicism for the 5p deletion in one of the parents.
oIf a parent is a balanced carrier of a structural rearrangement, the risk is substantially high. The risk should be assessed based on the type of structural rearrangement and its pattern of segregation.
• Chronic medical problems such as upper respiratory tract infections, otitis media, and severe constipation require appropriate treatment.
• Use the relatively good receptive skills to encourage language and communicative development rather than relying on traditional verbal methods.
• Early stimulation and introduction to sign language are effective means of developing communication skills (50% of children are able to use sign language to communicate).
• Behavior modification programs may be successful in managing hyperactivity, short attention span, low threshold for frustration, and self-stimulatory behaviors (eg, head-banging, hand-waving).
• Visual-motor coordination computerized training improves the visuospatial performance in a child affected by cri-du-chat syndrome

How to Avoid Cri Du Chat?

My Answer:
There is no known prevention. Couples with a family history of this syndrome who wish to become pregnant may consider genetic counseling.